Header bar uvimage editor header the header bar contains several menus and options for working with uvs view menu tools for, working with the editor and controlling how things are displayed. The drug benzyl benzoate used in antifungal preparations has a mutagenic compound, chamuvaritin, a benzyl dihydrochalcone that was isolated from uvaria chamae 10. Evaluation of invivo antisalmonella activity of uvaria. A new cytotoxic acetogenin, chamuvarinin 1, containing a tetrahydropyran ring with an adjacent bistetrahydrofuran ring, which corresponds to a novel carbon skeleton in this series, was isolated from the roots of uvaria chamae, together with the previously reported acetogenins squamocin 2, desacetyluvaricin 3, and neoannonin 4. Citation data is made available by participants in crossrefs citedby linking service. It has been reported that extracts of uvaria chamae have mutagenic effects. The leaves and roots of uvaria chamae are rich in natural. Pdf the roots of plumbago zeylanica plumbaginaceae and uvaria chamae annonaceae have been used in folklore medicine in the management of.
The extracts reduced the incidence of paw oedema from 0. A quantitative documentation of the composition of two powdered herbal formulations antimalarial and haematinic using ethnomedicinal information from ogbomoso, nigeria adepoju tunde joseph ogunkunle, tosin mathew oyelakin, abosede oluwaseyi enitan, and funmilayo elizabeth oyewole environmental biology unit, department of pure and applied. It is the goal of my research in particular, to elucidate both the effects and the mechanisms of action of the herbal medicine or complementary and alternative medicine cam using animal models of stressrelated diseases such as anxiety, depression, insomnia or learning and memory. Odewo, a taxonomist in the department of botany and microbiology, faculty of science, university of lagos, nigeria. For a more comprehensive list of citations to this article, users are encouraged to. Uvaria chamae, commonly known as finger root or bush banana is a climbing large shrub or. It is taken internally in the treatment of catarrhal inflammation of the mucous membranes. The majority of the ethiopian population is at risk of malaria largely caused by plasmodium falciparum. Nigeria is naturally blessed with both savannah and tropical rainforests vegetation and these offer a wide distribution of plants believed to possesses secondary metabolites which are responsible for treating or curing various diseases. Antiglycation, antioxidant, and cytotoxic activities of uvaria chamae. Research article antibacterial activity of chalcone and. Graviola inhibits hypoxiainduced nadph oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity. The potentials of uvaria chamae as an antidiabetic and hypolipidemic drug candidate are thus tested. Bmc complementary medicine and therapies home page.
Antimicrobial susceptibility tests were performed against several multidrugresistant bacteria using the mueller hilton well agar. Chamuvarinin, an acetogenin bearing a tetrahydropyran ring. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your bloodpressure extensively. Download fulltext pdf download fulltext pdf download fulltext pdf download fulltext pdf evaluation of invivo antisalmonella activity of uvaria. Phytochemical composition, antioxidant and antibacterial. Phytoconstituants of two extracts of uvaria chamae tannins, flavonoids, and phenols were also.
Haematological effect of ethanolic extract of uvaria. Uvaria chamae annonaceae, is an essential oil bearing plant. Beauv annonaceae offers alternative treatment for diabetes mellitus. Really good app for what it does, has almost everything we need compared to the big pdf editors like adobe acrobat. Access is allocated within two business days of purchase and lasts one year. Issued as a pdf on the internet, it contains basic information on over 250 species of plants used for food.
Uvaria chamae is a climbing shrub or small tree growing up to 4 metres tall328. Comparison of commercially available multiplex rat cytokine methods. Title african flowering plants database publication author website. The study aimed at evaluating antidiabetic activity of the ethanolic root extract of u. However, very few of them have so far been evaluated. This study presents antimicrobial properties of uvaria chamae roots, commonly used for the.
Antidiabetic effects of the ethanolic root extract of uvaria chamae p. Their constituents were extracted and then fractionated in order to isolate the active ingredients. Haematological effect of ethanolic extract of uvaria chamae on monosodium glutamate msg induced toxicity in spraguedawley rats ibukun o. Uvaria chamae is one of such plants used traditionally to treat diabetes mellitus and other conditions such as. The potentials of uvaria chamae as an antidiabetic and hypolipidemic drugcandidate are thus tested. The ones marked may be different from the article in the profile. Chemical constituents of clerodendrum splendens lamiaceae. Diabetes mellitus has been a menace to mankind from time immemorial. Evaluation of invivo anti salmonella activity of uvaria. This study aimed to produce scientific data on in vitro and in vivo efficacy of uvaria chamae, lantana camara and phyllantus amarus on multiresistant salmonella spp isolated in. This work will be of significant interest to scientists, researchers, medical practitioners, pharmacologists, ethnobotanists, horticulturists, food nutritionists, agriculturists, botanists, herbalogists. Uvaria chamae was extracted with ethanol, and administered orally to rats at doses ranging from 200 to 5000 mgkgday for 28 days while distilled water was administered to the control group, the survived animals 43 %, were then euthanized, and blood collected for biochemical and haematological markers. Graviola inhibits hypoxiainduced nadph oxidase activity.
This study aimed to produce scientific data on in vitro and in vivo efficacy of uvaria chamae, lantana camara and phyllantus amarus on. Uvaria chamae is a medicinal plant that is used in many parts of the world in the treatment of diabetes, and other diseases. Pdf phytochemical composition and biological activities of uvaria. Fresh uvaria chamae leaves and roots were air dried, pulverized and extracted. In this study, we evaluated the acute and subchronic oral toxicity and safety of the aqueous root extract of uvaria chamae in. This study presents antimicrobial properties of uvaria chamae roots, commonly used for the treatment of various infections in south benin. Pdf phytochemical composition, antioxidant and antibacterial.
The finding of the study will help inform decision regarding improved policy responses in screening of highrisk population and public health management of the disease across the rural communities within the region and in nigeria as a whole. Molecular mechanisms of inhibition of streptococcus. This page was last edited on 19 august 2018, at 12. Several researches have been carried out in order to explore and identify the chemical compositions responsible for various pharmacological. Beauv and clerodendron splendens a cheval are known to have various medicinal and therapeutic properties.
Issued as a pdf on the internet, it contains basic information on over 250 species of plants used for food in benin. Evaluation of antitrypanosomal and anti inflammatory. This multicompendium is a comprehensive, illustrated and scientifically uptodate work covering more than a thousand species of edible medicinal and nonmedicinal plants. The purpose of this study was to evaluate the antioxidant activity of compounds isolated from clerodendrum splendens leaves. New dihydrochalcones and flavanones from uvaria angolensis. In vitro antiradical and antisalmonella activities of. Isolation and characterization of compounds from the stem bark of uvaria rufa annonaceae 53 experiments of hmbc as shown in a and hh cosy in b established the final structure of benzyl benzoate. Pdf antidiabetic effects of the ethanolic root extract. To learn about our use of cookies and how you can manage your cookie settings, please see our cookie policy.
Beauv and clerodendron splendens a cheval are known. Files are available under licenses specified on their description page. The mutagenic effects of chamuvaritin, a dihydrobenzylchalcone isolated from uvaria chamae, were investigated using salmonella typhimurium tester strains ta92, ta9498, ta1001535, ta1537 and ta1538. Uvaria is a genus of flowering plants in the soursop family, annonaceae. Department of medical biochemistry, college of medical sciences, university of benin, benin, nigeria a327. Create your own buttonbadge designs online with the buttonmaker2, powered by smart grafx. Antibacterial activity of chalcone and dihydrochalcone.
In ethiopia, people use different plant species to treat malaria. Pdf in vitro antisickling activities and phytochemical evaluation of. Medicinal plants used by the people of nsukka local. Uvaria chamae is a plant with both medicinal and nutritional values. The genus is characterized by a combination of features, including stellate hairs, generally valvate sepals, partially or fully. Improving the production of podophyllotoxin in hairy roots. The resistance of the parasite to existing drugs is the main challenge in the control of the disease and thus new therapeutic drugs are required. In vivo and in vitro studies carried out by many researchers have shown that. Phytochemical compositions in some nigerian medicinal. This study aims to analyze the chemical compounds and evaluate the antiradical and antisalmonellaactivities of extracts from sarcocephalus latifolius, lannea barteri, uvaria chamae, parkia biglobosaand khaya senegalensis using respectively standards phytochemical methods, phosphomolybdates reduction method and micro dilution method in liquid medium associated.
Unona macrocarpa vahl unona macrocarpa vahl ex dunal uva chamae kuntze uva cristata kuntze uva cylindrica kuntze uvaria cristata r. Histopathological examination of the pancreas, liver. Pdf in the present work phytochemical composition, antioxidant and antibacterial. An ethnobotanical survey was carried out between march 2016 and august 2016 to obtain relevant information about medicinal plants used in the treatment of malaria in nsukka local government area of enugu state, southeastern nigeria. Uvaria chamae, commonly known as finger root or bush banana is a climbing large shrub or small tree native to tropical west and central africa where it grows in wet and dry forests and coastal scrublands.
This cited by count includes citations to the following articles in scholar. Antidiabetic and hypolipidemic activities of hydroethanolic root. Pdf various parts of uvaria chamae are used by traditional medicine. Enjoy unrestricted access to all content and features, including.
If you experience drowsiness, dizziness, hypotension or a headache as sideeffects when using uvaria chamae medicine then it may not be safe to drive a vehicle or operate heavy machinery. Phytochemical composition, antioxidant and antibacterial activities of root of uvaria chamae p. Effects of uvaria chamae root extracts on cortisol, insulin, and testosterone in normal and streptozotocininduced diabetic rats f. Evaluation of the antiplasmodial properties of selected. The drug benzyl benzoate used in antifungal preparations has a mutagenic compound. Create your own button designs online with the buttonmaker2, powered by smart grafx. The common name refers to the fruit growing in its small bunches. However, research is needed to ascertain the beneficial and adverse effects of the consumption of the extract. A quantitative documentation of the composition of two. The leaves of clerodendrum splendens are used in traditional medicine by indegenous people to treat shingles, spleen in children, asthma, rheumatism, ulcers and malaria. By closing this message, you are consenting to our use of cookies. Antidiabetic effects of the ethanolic root extract of. The aim of this study was to investigate the effects of caralluma russeliana stem extract on some physiological. Pharmacists also advise patients not to drink alcohol with.
Phytochemical composition and biological activities of uvaria. Cytotoxicity was determined using the sulforhodamine b method, and the. The phytochemical was mutagenic in tester strains ta98 and ta100 and required activation by the hepatic s9 microsomal enzyme preparation. Antibiofilm activity of prosopis africana and uvaria chamae extracts against. Uvaria chamae annonaceae, phyllantus amarus phyllantaceae and lantana camara verbenaceae are empirically alleged to be used as beninese medicinal plants in the treatment of salmonellosis. All structured data from the file and property namespaces is available under the creative commons cc0 license. Full text effects of caralluma russeliana stem extract. Pdf diabetes mellitus has been a menace to mankind from time immemorial. Multistage carcinogenesis in the urinary bladder, british medical bulletin, volume 36, issue 1, 1 january 1980, pages 3946, s. Annonaceae is a speciesrich genus of woody climbers and scandent shrubs, widespread in wet tropical forests in africa, madagascar, continental asia, malesia, northern australia and melanesia. Please note that this is a trial program and may end. Pdf evaluation of invivo antisalmonella activity of. Genetic transformation was confirmed by epifluorescence and plagiotropic hairy root growth in absence of growth regulators. The generic name uvaria is derived from the latin uva meaning grape, likely because the edible fruit of some species in the genus resemble grapes.
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